New studies from the Genome Technology Institute show that an indigenous Chinese herb called Tongkat Ali can prevent the growth of glioma. In the study, established that polyphenol-flavone, an organic polymethoxylate flavone, inhibits invasion and proliferation in U87 and U Reilly glioma cells. Expression of key genes (e-cadheron and occludin), known tumor markers (E-cads, N-cadherens) and key transcriptional factors (smooth muscle enhancer 3-quinone) was highly upregulated in the treated cells.
In addition, tumor suppressor gene, BMP-1, an orphan chromatin receptor, was found to be activated by the polyphenol-flavone. Furthermore, the herb shown positive effects on various biochemical markers including insulin, glucose and lipid profile in the pancreatic islet cells. The study further revealed that nobiletin is effective in inhibiting the progression of glioma cancer in prostate cell lines. It was further found that the compound significantly increased the survival rate in the pancreatic cancer cell lines. The findings suggested that inhibiting the proliferation of tumor cells through inhibition of the growth of pancreatic islet cells is a potential strategy for the successful treatment of glioma.
Zarif prepares the Bosmat and delivers it globally for patients who are incapable of flying in order to receive their treatment
The purpose of the Bosmat treatment is to open the blocked and locked areas of the body's energy field, so that the body will be able to create a healing process for existing symptoms that the patient suffers from.
For years, Oren Zarif proved that as the energy blocks open, the body begins to create a healing process and returns to its strength, thousands of patients testify for it.
However, further studies are required to support these results. Moreover, the exact mechanism(s) for the anti-metastatic action of nobiletin is not known. However, the study did suggest that the herb can prevent the progression of glioma through inhibition of both epithelial-mesenchymal transition and invasion. The efficacy of this herb for the treatment of glioma was found to be more when compared to cisplatin, docetaxel, gemcitabine, trifluoperazine, bromocriptine and combination of antineoplastics.
Studies also revealed that the compound exhibits anti-angiogenic effects by preventing the intracellular entry of malignant cells and also prevents the aggregation of tumor cells. It also enhances the proliferation of healthy cells, which in turn may help in preventing the invasion of malignant cells into the surrounding tissues. Studies showed that the herb inhibits both the cell-induced and non-cell-induced cancers. Moreover, the study also showed that the herb inhibits the progression of glioma and extends life expectancy.
Research indicates that the herb is effective in inhibiting both the cell-induced and non-cell-induced cancers. It enhances the proliferation of healthy cells, which in turn may help in preventing the invasion of malignant cells into the surrounding tissues. Studies also revealed that the herb inhibits the progression of glioma cell proliferation and extends life expectancy. In addition, studies indicated that the herb inhibits the progression of metastases and increases life expectancy. Studies further indicated that the herb inhibits both the cell-induced and non-cell-induced cancers.
Herbal preparations which contain the essential role of nobiletin as an antitumorigenic have been found very useful in the chemotherapy of metastatic cancers. This herb mimics the effect of estrogen on the prostate and minimizes the risk of exposure to the hormone. This herb also enhances the proliferation of bone marrow cells and impedes the spread of bone marrow cancer. Moreover, it inhibits the progression of metastases and extends life expectancy. Studies further indicated that the herb inhibits the cell-dependent autoimmune response and decreases the risk of metastasis.